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Death by De-aging
- 306 statements
- 58 feature instances
- 27 referencing feature instances
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The Fountain of Youth seems an attractive idea, especially for the elderly; you get to wind back the clock and prolong your life. However, much like a drug, it can come with dangers if overdosed. If it has a continuous effect, the youth could make someone so young they regress to before they were born, becoming a fetus exposed to the world and at severe risk of dying. Or worse, regressing beyond that to the point that they don't even exist! Maybe it's because someone spent too much time in the Fountain of Youth, causing it to go horribly right. Or the youth continues to decrease someone's age even outside of it. If someone suffers from Merlin Sickness, this might be how it ultimately kills them. Could be considered a form of Harmful Healing, with the "healing" part being healing away age. When someone's birth is literally undone instead of reverting before it, it's a Ret-Gone situation. Contrast Rapid Aging, where someone rapidly ages and can be at risk of becoming too old to live rather than too young, or No Immortal Inertia, where someone reverts to their true ancient age and dies because of it. This might be part of what makes the Devolution Device so dangerous, though it usually "just" sending someone back down the Evolutionary Levels. |
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In the Rainbow Butterfly Unicorn Kitty episode "Fountain of Too Much Youth", Miguel was at risk of dying in this way after going in the fountain of youth. This was inverted in that same episode when Felicity fed him stinky cheese which aged him to an elderly condition. Later, he was returned to normal. | |
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The Man from U.N.C.L.E.: "One of Our Spies Is Missing" involves a biochemist who has discovered the secret of restoring youth, which he uses to restore retired statesman Sir Norman Swickert back to vitality to carry on his career. However, the process puts a considerable strain on the body, with him warning that if used too much the machine will "turn you into a boy, a dead boy". He later uses the same process to commit suicide rather than risk his technology being controlled by THRUSH. | |
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In The Land of What Might-Have-Been, Madame Morrible and a small cabal of fellow magicians try to gain immortality by stealing some of the Radiant Empress's blood... only to end up condemning themselves to spend eternity oscillating between various stage of youth. However, some of them learn how to devour the life-force of others in order to regain their adulthood, often killing their victims through this trope. In the finale, Morrible tries to pull this on Elphaba and even gloats about reducing her to embryonic goo, but only gets as far as reducing her to the age of eight before Dorothy intervenes, forcing Morrible to return the stolen energy. | |
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In The Dragon Doctors, this happened to most of the research team that discovered the Fountain of Youth, as well as every other living thing in the area. When the water is replicated and mass-produced, it includes a safeguard that stops the de-aging process at babyhood. | |
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Discussed in Dennis the Menace Strikes Again!; the Professor and Sylvester try to scam Mr. Wilson by selling him a root that can make people younger if they use it. Upon hearing about this, Dennis worries that if he uses too much of it, he'll become so young that he'll cease to exist. | |
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The Outer Limits (1995): In the episode "Last Supper", a Mad Scientist kidnaps an immortal woman in an attempt to manufacture a de-aging drug from her blood and heal the scars he gained the last time he captured her. Unfortunately for him, he miscalculates the drug's potency by a wide margin: after a brief Hope Spot in which he appears to have stopped in his twenties, he undergoes an extremely painful and Body Horror-iffic regression process, shrinking back through adolescence, childhood, infancy, before finally dissolving into a a puddle of cells. | |
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Red Dwarf: In Backwards, Lister has been transported to the Backwards Universe in order to reverse his fatal heart attack in the previous book. After living a long and happy marriage with his girlfriend Christine Kochanski, he is eventually due to be picked up by the Red Dwarf crew in his mid-twenties so he can be returned to the normal universe. Unfortunately, given the crew's predictable screw-ups, they end up missing the window to leave and getting trapped there for the next ten years, during which Lister and the Cat are regressed to teenagers. When they finally get to try again, Kryten is deeply concerned that if they screw up this time, they won't get to leave until the two organic crewmembers are toddlers, with any further mistakes resulting in them regressing even further and suffering "a very sticky end". Fortunately, they get it right on the second try. According to both Backwards and Last Human, Lister and Kochanski's children have already experienced this in the Backwards Universe; having been rescued alongside her husband in Last Human and having acclimatized to living in a Forwards Universe, Kochanski can now remember seeing her children shrinking down into infants before being pushed back inside her. |
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Saturday Morning Breakfast Cereal: In "Oops 4", this was apparently the plan from the start, except "the tape was in backwards". God doesn't take it well to learn that this has been going on for billions of years. | |
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Wonder Woman: The second Doctor Poison reveals that their grandmother, the original who fought Wonder Woman during the Golden Age, died when her reversing drug Reverso was used on her. Doctor Poison II states that she de-aged so quickly that she forgot how to stop the process from happening, until she reverted to a fetus and then nothing. | |
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Discussed and subverted in the Steven Universe episode "Steven's Birthday". Overusing shapeshifting to appear older ends up reducing Steven to infancy. The morning after he falls asleep as a baby, Connie finds the shirt that he was wearing lying around and is afraid that he regressed further into a zygote. Steven has actually returned to normal and just changed clothes before she woke up. | |
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In A Million Adventures, there is a time screen, under which time goes backwards. When it's accidentally left unattended, a rooster comes under the screen, turns into a chicken, then into an egg, then vanishes completely. Heracles, a pithecanthropus, crawls under the screen to eat that egg and barely escapes the same fate. | |
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In Johnny Test, Bling-Bling Boy threatens Johnny and Dukey with this after creating a de-aging ray gun, turning them into toddlers with the intent of reverting them to embryos. | |
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The Midnight Gospel: In the episode "Vulture with Honor", it's revealed that Clancy's property is right next to an extremely dangerous region of "Wobble" where space is divided into multiple dangerous colors, each one with its own lethal reality-warping effects. Steam-colored Wobble fatally regresses any organic lifeform touching it — or, as Captain Bryce puts it, it reverts them into "cream", which he demonstrates through Black Comedy Animal Cruelty. Soon after, he and Clancy find a looter who's been trapped in the purple Wobble for so long that his mind has completely snapped, prompting Bryce to Mercy Kill the guy by tipping him into the steam Wobble and allowing him to regress out of existence. | |
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Red Dwarf: Mentioned as a positive in "Backwards": naturally, people in the Backwards universe age in reverse, so the Red Dwarf crew quickly realize that they're going to start regressing if they stay long enough, ultimately resulting in the organic crewmembers being absorbed back into their mothers' wombs and dissolving into nothing... but Rimmer and Kryten don't actually regard it as death and believe that it will ultimately result in all humanity merging into "one glorious whole". Lister, who already considers Rimmer to be "one glorious hole", is not convinced. Referenced in "Pete, Part 2", when Kochanski warns that carelessly playing around with the Time Wand could end up transforming Lister and the others into sperm. The Cat's only objection to this is that none of his suits will fit. |
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Marvel Universe: Drom the Backwards Man is a one-shot villain who was born in the body of an old man and aged backwards. He attempts to stop this trope by absorbing life energy from others with a magical mirror, but when the mirror is shattered during Drom's battle with Spider-Man and Iron Fist, he rapidly de-ages into a newborn baby and then disappears. In Generation M, Sally Floyd's daughter Minnie was a mutant born with the power to reverse her age. Unfortunately, as a baby, she had no control over it and regressed until she had the body of a six-month-old at age four. This ended up killing her, leaving Sally severely depressed. Spider-Man: Silvermane, an 80-year-old Maggia crime lord, fears death due to his age and blackmails Dr. Curt Connors into making a Fountain of Youth serum with the aid of a newly discovered mystical tablet. It works too well, and he ends up apparently being de-aged out of existence... until his next appearance, that is. (In truth, the serum rapidly ages him from pre-birth into his forties, which is what he wanted in the first place.) A similar incident occurs in Spider-Man: The Animated Series, but with less fatal results (he is merely reduced to infancy). |
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In the Stargate SG-1 episode "Past and Present", SG-1 stumbles upon a planet were everyone has amnesia, and also, there are no old people. They eventually learn that the rogue scientist Linea has developed a way to reverse the aging process. Unfortunately, a gas cloud escapes containment and spread across the planet causing everyone to regress some 40 to 50 years. Thus, the people they met are the elders, while anyone younger than 50 or so years met their demise through de-ageing. | |
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Wicked Science: In the very first episode, Elizabeth tampers with Toby's experiment to clone a dinosaur, which causes a Tyrannosaurus rex to grow to adulthood overnight. In the end, Toby manages to de-age the T. Rex past its birth, until it's a pinhead-sized lump of cells. | |
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Goosebumps: A variation involving Mental Time Travel occurs in The Cuckoo Clock of Doom, as the protagonist is gradually sent further and further into his own past by the titular object and has to find a way to reverse the process before he disappears. After managing to undo the curse and return to the present, he finds that his abusive little sister has accidentally been subjected to the same treatment and erased from history as a result. A variant featuring physical regression appears in the Give Yourself Goosebumps novel The Knight in Screaming Armor. In one plot thread, you and your two friends find themselves falling foul of yet another time-controlling clock and regressing into infancy over the course of the next few minutes. With your friends having mentally regressed as well, it's up to you to stop the clock before it rewinds you to a time before you were born. You manage to stop regressing and restore your friends to their former ages, but for no adequately explored reason, it doesn't restore your age, unfortunately; as such, this plot-line ends with you being cuddled by one of your cousins as you bawl your head off. For now, you're still alive, but it's never made clear what'll happen to you next — if you're stuck reliving your entire life from square one, if you're permanently a baby, or if you really will suffer the Death by De-aging you saved your cousins from. |
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In the Call of Cthulhu adventure "The Curse of Chaugnar Faugn" from the supplement Curse of the Chthonians, the Time/Space Machine is able to de-age an object or creature, moving it back in time and making it younger. If a creature is moved back to before it was born, it will cease to exist. | |
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The Shadow of the Demon Lord supplement book Occult Philosophy has several new spells as well as rare high-level spells, including the Alchemy spell "Brew Longevity Potion", which allows one to brew an Elixir of Life that can make any who consumes it younger. However, there is a risk that one may grow too young and end up turning into a tiny embryo that dies a few rounds later. | |
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FTL: Faster Than Light has a random event where the crew of your ship encounter Zoltan monolith known as "the Great Eye". Should you pull the ship closer, several outcomes might happen, and one of them is your crewmember rapidly aging in reverse until they disappear, with the rest of your crew hoping that they merely transcended physical existence instead of simply ceasing to exist. De-aged crewmembers also cannot be brought back even with the Clone Bay. | |
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In the Class of the Titans episode "Time Enough for Everything", Cronus, villainous god of time, gets his hands on the timepiece of Zeus and, among other things, uses its power to de-age Jay out of existence. Fortunately, all the time travel shenanigans get undone by the end of the episode. | |
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In Wishmaster 2: Evil Never Dies, the wounded thief who accidentally frees the Djinn is so terrified by his appearance and the predicament he's been left in that he wishes that he was never born. The Djinn grants his wish in horrific fashion, putting him through painful devolution until he eventually vanishes from existence. | |
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The Real Ghostbusters: In the episode "Three Men and an Egon", Egon gets caught in the proton beams along with a ghost that ages in reverse, causing them to exchange aging processes. As a result, Egon begins to de-age from an adult to a baby at an alarming rate. Ray, Peter, Winston, and Slimer have to find the ghost and reverse the process before Egon disappears. | |
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Darker than Black: Amber's Time Master powers come at the expense of making her younger with each use. In the finale, she makes a Heroic Sacrifice to send Hei back in time to save the Contractors, leaving only her clothes behind. | |
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JoJo's Bizarre Adventure: Stardust Crusaders: Alessi's Stand Sethan is a shadow that de-ages whoever's in it within mere seconds. A woman unfortunate enough to spend too long under the shadow is reduced to a fetus, making Polnareff's encounter a Race Against the Clock to incapacitate Alessi before this kills her. Fortunately, Jotaro ends up knocking him out cold and she goes back to her natural age with no ill effects beyond short-term memory loss. | |
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My Hero Academia: Eri's Quirk lets her "rewind" living things to a previous state, including to the state in which they never existed. She accidentally did this to her father when her Quirk first awakened, and the bullets that the Shie Hassaikai are producing work by rewinding the people they shoot to a state from before humanity first developed Quirks. In fact, it is this Quirk that finally causes All for One's death: during the final battle, AFO uses a copy of Rewind to negate a fatal injury and gain immense regenerative abilities, hoping that this last-ditch effort will give him enough time to reach and re-brainwash a rebelling Tomura. Instead, the heroes' efforts and attacks rapidly cause him to de-age until he disappears without having accomplished his goal. | |
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Magellan: A woman who obtained de-aging powers from a genie nearly does this to hero Gola Beh. While she's stopped before Gola de-ages into non-existence, Gola still winds up as a teenager from it. | |
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Requiem Vampire Knight: On the hellish afterworld of Requiem, people (or at least vampires) age backwards. Hence, especially long-lived characters such as Lord Cryptos look like babies, and it is inferred he will continue de-aging until he truly dies. Only members of Dracula's bloodline possess real immortality. | |
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In the Regular Show episode "Terror Tales of the Park II", Margaret tells a ghost story of how Mordecai, Rigby, Eileen, and herself joined a party bus, only to soon discover that everyone was rapidly aging to the point of turning to dust. The four try to escape but the bus driver laughs as he refuses to stop. They manage to get the bus into reverse to try to undo the rapid aging, but they de-age too far into young adults, then teenagers, then children, then babies. They find a hatch on top of the bus and jump off to freedom, but they keep de-aging anyway until they disappear into nothing. The bus, meanwhile, turns to dust. | |
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Crops up in an unusual way in Nutty Professor II: The Klumps. After realizing that he needs to reabsorb Buddy Love in order to restore his own collapsing intellect, Sherman Klump fills a rubber ball with his prototype youth serum and tricks Buddy into chasing it like a dog — exposing him to the serum when he manages to catch it in his mouth. Regressing to a toddler, Buddy manages to escape the room after further antics... only to continue regressing into a puddle of transparent blue slime that continues fleeing the building. Following a chase scene, the slime finally evaporates after being outside for too long, at first making it look as though the story is going to conclude on a Downer Ending — up until the last few traces of Buddy end up in a fountain, which Sherman drinks from to regain his mind. | |
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The DCU: Legion of Super-Heroes: In Adventure Comics #338, the Time-Trapper provides his agent Glorith with an hourglass that emits "devolutionary radiation", causing anyone who touches it without special protective gloves to regress in age until they become "protoplasmic slime... the source of all life". Fortunately, when Glorith tricks the Legionnaires into touching the hourglass, they are merely de-aged to infancy thanks to the presence of a "Fountain of 1,000 Chemicals". The Time-Trapper punishes Glorith for her failure by tricking her into touching the hourglass without her gloves, and then tries to complete the Legionnaires' retrogression into protoplasmic blobs... but not before exploiting their youthful innocence and still-formidable powers for his own criminal gain. Wonder Woman: The second Doctor Poison reveals that their grandmother, the original who fought Wonder Woman during the Golden Age, died when her reversing drug Reverso was used on her. Doctor Poison II states that she de-aged so quickly that she forgot how to stop the process from happening, until she reverted to a fetus and then nothing. |
|
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Death by De-aging | |
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Discussed in the Rugrats episode "Back to School"; when Didi says she's going Back to School (specifically, to college to master her degree in child development), Angelica overhears and tricks the babies into thinking that everything is going backwards. The babies then overhear Stu telling Dil it's time for him to go back to the hospital, making them believe that Dil is going to be unborn (Stu was really taking Dil to the hospital for a check-up). They also worry that it will eventually happen to them. | |
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Futurama: In "Teenage Mutant Leela's Hurdles", the crew visits a Neptunian spa so the rejuvenation tar can make Professor Farnsworth less of an obnoxious old man. They end up getting in the tar and turning into teenagers (Farnsworth becomes middle-aged). He attempts to cure them of the tar with bacteria (except Leela who chooses to stay a teen). Not only does it fail, but the bacteria starts spreading the tar, causing them to become progressively younger over time. The crew is in a rush to get to the Fountain of Aging before they regress to pre-life, then death and non-existence. By the time they actually get to said fountain, the affected individuals are fetuses save for Farnsworth, Zoidberg, and Bender, who are a toddler, coral polyp, and blueprint disc respectively. | |
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In Phase V of Zenith, Dr. Michael Peyne is cursed with a nice dose of Merlin Sickness by the Lloigor, just so he has enough time to appreciate the reality-warping apocalypse he's caused. Worse still, it actually seems to pick up speed over time. Eventually, writing the final pages of his Apocalyptic Log in a childish scrawl, a very young Peyne crawls into bed for a nap; when Ruby arrives to say goodbye to him, he's just a baby draped in his adult-sized shirt. Gloating, Ruby takes baby Peyne to the balcony to give him one last look at the world he created, whereupon he floats away, shrinking down into a fetus, then an embryo, before he finally vanishes into nothing. | |
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Death by De-aging | |
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In WEIRD World 1995, Dr. Abby O'Reardon has invented a youth serum, but hasn't yet developed the antidote that can stop the rejuvenation process before this trope ensues. As such, when she decides to test it on the obnoxious Dr. Mayhew without his permission, he's more than a little bit concerned; however, after three hours with no effects, he's convinced that the serum didn't work and feels safe enough to leave the lab... only to end up calling Abby in a panic when he finds himself back in his twenties and getting steadily younger. By the time he returns to the lab, he's a child and clearly convinced that he's just about to regress out of existence, judging by the terrified whimpering. However, Abby then reveals that she's had an antidote all along and she was just fucking with him. She still takes her time in curing him, though, just so she can adopt a baby. | |
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Spider-Man: Silvermane, an 80-year-old Maggia crime lord, fears death due to his age and blackmails Dr. Curt Connors into making a Fountain of Youth serum with the aid of a newly discovered mystical tablet. It works too well, and he ends up apparently being de-aged out of existence... until his next appearance, that is. (In truth, the serum rapidly ages him from pre-birth into his forties, which is what he wanted in the first place.) A similar incident occurs in Spider-Man: The Animated Series, but with less fatal results (he is merely reduced to infancy). | |
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Robot Chicken: One sketch has Ra's al Ghul bragging to Batman that the Lazarus Pit makes him functionally immortal. He enters as an old man and surfaces around middle-aged. Batman responds by refusing to let him climb out, forcing him to revert to a teenager, then a child, then an infant, and then.... | |
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Curious example in the Celebrity Deathmatch fight of the Three Stooges vs. the Three Tenors that makes use of the time machine. Larry gets de-aged into a sperm and sacrifices himself by jumping into Pavarotti's eye, distracting him and allowing the Stooges to win the match. The fight also had an example of the opposite concept: one of the Tenors being aged into a corpse. | |
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A mental variant occurs in the Young Justice (2010) episode "Bereft", in which the team is hit by a psionic attack which erases the last few months of their memory. For the vat-grown Superboy, that's all the memory he has, so they end up with a mindless berserker. | |
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Discussed in One Piece Film: Z when Ain mentions being able to use her Devil Fruit powers to regress people out of existence by touching them enough times, thus threatening an already de-aged Robin into not fighting back further. | |
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Legion of Super-Heroes: In Adventure Comics #338, the Time-Trapper provides his agent Glorith with an hourglass that emits "devolutionary radiation", causing anyone who touches it without special protective gloves to regress in age until they become "protoplasmic slime... the source of all life". Fortunately, when Glorith tricks the Legionnaires into touching the hourglass, they are merely de-aged to infancy thanks to the presence of a "Fountain of 1,000 Chemicals". The Time-Trapper punishes Glorith for her failure by tricking her into touching the hourglass without her gloves, and then tries to complete the Legionnaires' retrogression into protoplasmic blobs... but not before exploiting their youthful innocence and still-formidable powers for his own criminal gain. | |
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Dorkly Originals: The Most Horrifying Finish Move in Mortal Kombat has Sonya mess up the "Babality" on Sub-Zero, turning him into a fetus which promptly dies because of it. Everyone who sees it is disgusted, even Scorpion and Shang Tsung. | |
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My Life as a Teenage Robot: Due to complications involving Time Dilation in "Good Old Sheldon", Sheldon ends up becoming an old man. Dr. Wakeman manages to create a de-aging mechanism based on Jenny's movements, however, she's still fighting once he gets back to his normal age. By the time he's an infant, Dr. Wakeman warns Jenny not to make any movements lest Sheldon be reduced to a zygote, and has to age another 15 years to get back to normal. | |
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The Star Trek: The Animated Series episode "The Counter-Clock Incident" features the crew accidentally getting stranded in a backwards universe, in which the "old" ultimately die at the nadir of infancy; for good measure, in the novelization of this episode, Spock admits to being rather curious as to how obstetrics work in this reality. Later, while speeding towards a nova star that can return them to their universe, the crew of the Enterprise begin to experience the effects of reverse Time Dilation: instead of observing the passage of time at a much slower speed than anything outside the ship, they experience it at a drastically accelerated rate — and because people age in reverse in this reality, the crew find themselves getting younger and younger until they run the risk of ceasing to exist. Worse still, the regressed also lose access to their adult knowledge, leaving them with progressively fewer qualified crew-members to get them to the nova star in time. Fortunately, there's a septuagenarian commodore and his wife on board to save the day. | |
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Codename: Kids Next Door: The Delightful Children from Down the Lane threaten to do this by setting the dial on their age-changing ray to "age 0", saying it will make the Kids Next Door vanish forever when they use it on them. They never actually get the chance to try it, though. Leaky Leona tried to kill the Kids Next Door by spraying them with the waters of the Fountain of Youth in order to get rid of witnesses. She was stopped by the Delightful Children from Down the Lane when they destroyed the Fountain. |
|
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Sam & Max: Freelance Police: In the episode "Moai Better Blues", Sam & Max encounter various people who had gone missing years ago that have turned into babies from drinking the fountain of youth. Among them is Jimmy Hoffa, who blocks the way into a cave the need to access. In order to get rid of him, Sam & Max have to trick him into drinking more of the fountain of youth, causing him to vanish. | |
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In the T.U.F.F. Puppy episode "Pup Daddy", a gadget called the Young Gun causes the agents sans Dudley as well as Snaptrap and his gang to gradually de-age from teen to toddler to baby. Dudley has to return them to normal before they age backwards too much that they cease to exist. | |
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A variant featuring physical regression appears in the Give Yourself Goosebumps novel The Knight in Screaming Armor. In one plot thread, you and your two friends find themselves falling foul of yet another time-controlling clock and regressing into infancy over the course of the next few minutes. With your friends having mentally regressed as well, it's up to you to stop the clock before it rewinds you to a time before you were born. You manage to stop regressing and restore your friends to their former ages, but for no adequately explored reason, it doesn't restore your age, unfortunately; as such, this plot-line ends with you being cuddled by one of your cousins as you bawl your head off. For now, you're still alive, but it's never made clear what'll happen to you next — if you're stuck reliving your entire life from square one, if you're permanently a baby, or if you really will suffer the Death by De-aging you saved your cousins from. | |
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The minor villain Loco from MÄR uses a set of Darkness ÄRMs that allow her to immobilize enemies and then inflict agonizing pain on them through a straw doll, at the cost of making her de-age afterwards. She received them from a previous user who de-aged into nothing immediately after passing them to her. In the anime, Loco comes close to suffering the same fate but stops at baby age. | |
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The De-Age spell in the Lamentations of the Flame Princess supplement Better Than Any Man can cause this, among various other potential side effects; what makes it particularly risky is that the amount of de-aging it causes is highly random — a single casting can remove anything from one to over thirty years. | |
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Charlie and the Great Glass Elevator: Willy Wonka has managed to develop Wonka-Vite pills, which decrease someone's age by 20 years exactly. Upon being offered some by Wonka, Grandma Josephine, Grandpa George and Grandma Georgina take four, despite some of them barely being in their eighties. Worse still, Josephine is younger than eighty, leaving her to regress to minus years and vanish out of existence; this leads to her reappearing in Minusland as what is essentially a preborn ghost at risk of becoming the prey of Gnoolies. | |
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Family Guy: In "Yug Ylimaf", Brian's screwing with Stewie's time machine causes the time to run backward and at an accelerated state. Stewie becomes panicked when he starts to revert in development, and the two are in a race against time to set things back to the normal before Stewie is returned to the womb and gets unmade. | |
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This is narrowly avoided in House of Anubis: when Alfie is cursed to de-age, he becomes a pre-teen, and then a baby, with the implication being that if Nina, Fabian and Patricia weren't able to stop the curse in time, he would've been de-aged out of existence. | |
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The Mask: In the episode "Little Big Mask", the Mask creates an anti-aging cream and uses it on himself... only for Stanley find that the effects can't be stopped, not even by the Mask's reality-warping powers, leaving him and Peggy Brandt struggling to create an antidote before he regresses out of existence. Towards the end of the episode, Peggy wakes up in the hospital to find that there's nothing left of Stanley but empty baby clothes, and tearfully assumes that this trope has come to pass; to her immense relief, it turns out that Stanley had just been taken away for a check-up and is a perfectly healthy infant... but unfortunately, he's still getting younger, and by now he's too young to wear the Mask — leaving him unable to help in what might be his final minutes. Fortunately, Peggy is able to improvise a cure before it's too late. | |
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Tales to Astonish: In "What Was the Strange Power of Simon Drudd!!", the eponymous villain decides not to share his youth serum with the world once he's developed it, instead opting to use it on himself so that he can become an immortal and eventually go on to rule the world. For good measure, Drudd even locks his assistant Bentley in the freezer just so he won't be able to stop his bid for immortality. Unfortunately for Drudd, once the Transformation Exhilaration stage is finished, it turns out that the serum is a lot stronger than anticipated — and can't be stopped. With Bentley still locked in the freezer, Drudd is left helplessly regressing to infancy, before quietly vanishing out of existence and leaving behind only empty clothes. | |
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In Pokémon Journeys: The Series, as a result of Bizarro Universe Team Rocket's meddling, the god of time Dialga has a Superpower Meltdown that threatens an entire universe with this, requiring Ash and his friends to summon the Top God Arceus for Divine Intervention after they're all reverted to kindergarteners and their mons into eggs. | |
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The Star Trek: The Next Generation episode "Too Short a Season" features the famous now-elderly Admiral Jameson having discovered a drug on Cerberus II which can restore youth but carries a high mortality rate at the best of times. He initially planned on slowly taking it with his wife, but when his old enemy Karnas organizes a hostage situation with the intention of luring Jameson into a confrontation, the Admiral takes both doses so that he'll be young enough to face him. Despite initially promising results, the drug eventually causes him to regress to adolescence (younger than he was when he met Karnas), with the strain of the changes killing him shortly afterwards. | |
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