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Mystical Plague

 Mystical Plague
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 Mystical Plague
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Mystical Plague
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When The Plague is brought about not via natural evolution or the machinations of science, but is instead created through the supernatural powers of a person, creature, or group, whether by accident or design.
In classical works, Mystical Plagues are brought about by the gods or God to punish society for some collective sin. The plague invites some investigation into who offended the divine and how to make up for the damage.
Fantasy uses of the trope are less positive. Perhaps a Necromancer is summoning dark magic to bring about the Zombie Apocalypse, worshippers of the God of Disease call upon their master to bring vengeance upon their enemies, cults of Eldritch Abomination obtain Lovecraftian Superpower or a shaman uses a forbidden curse in the vain hopes that it keeps his people from being wiped out. Whatever the reasons behind it, the human use of disease-based magic is always seen as an evil act for the sheer amount of suffering it can bring about.
Mystical Plagues need not be limited to just attacking the physical being of those who contract it, and thus are not limited to the standard vectors of transmission of common illnesses. A curse may be designed to infect the spiritual essence of a creature, or even to only infect other magic users as they cast spells of their own. While this versatility may seem to make a magically created plague more reliable than other types, it is still not uncommon for the caster who created it to be killed as well, either directly by being infected themselves, or in the aftermath that the disease's spread causes.
A subtrope of The Plague. Compare Synthetic Plague, The Virus, and Depopulation Bomb. Can overlap with Fisher King, in cases where the Mystical Plague is caused by the actions of a kingdom's ruler. May also overlap with Maybe Magic, Maybe Mundane, or In Mysterious Ways, if the exact cause of the problem is either not understood or not explicitly stated.
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2024-04-09T04:17:29Z
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2024-04-09T04:17:30Z
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Everfree Infection AU (Fanfic)
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DBTropes
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Angel Mage: The country of Ystara is destroyed by one of these, the Ash Blood plague, which as the name implies turns the blood of the afflicted to ash. One third of the victims instead turn into monsters called "beastlings".
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The Blight disease spread by the Darkspawn in Dragon Age is said to be a curse by the Maker upon the Tevinter Magisters, who turned into the first Darkspawn themselves under its influence. It twists and eventually kills everything infected by it. The sites of especially large darkspawn raids have been hit so hard that dead bodies won't rot because all insects and bacteria have already been killed.
In the Dragon Age: Origins DLC "Warden's Keep", Avernus' research into the Taint suggests that it's alien to Thedas, with its true origins unknown even to the denizens of the Fade, such as Spirits and Demons. Avernus believes that the key to understanding it is tied into whatever caused the corruption of the Black City.
Dragon Age: Inquisition reveals that Red Lyrium is lyrium tainted by the Blight. This has disturbing implications: since the Blight only affects living things, lyrium is alive, meaning using it is just another form of Blood Magic. The fact that Red Lyrium is found in the Primeval Thaig, which predates the First Blight, hints that the Blight existed long before the Darkspawn appeared. It didn't start with them.
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The Silmarillion mentions a plague apparently sent by Sauron to weaken Gondor so he could regain control of Mordor.
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Octopath Traveler II: Trousseau concocted a deadly poison with the help of the Shadow and released it into the air above Healeaks to wipe out its entire population as part of his plan to "save" humanity by killing everyone. In Castti's final chapter, he strikes again, but Castti is able to create a cure and save those who got infected after having to kill Trousseau.
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In Bloodborne, the Scourge of the Beast is a plague which transforms people into werewolf-like creatures called Beasts. The twist is that the organization that's supposedly combating the Scourge, the Healing Church, is actually the cause of said plague, and that their supposed panacea blood ministration (as blood of a Great One) causes people to turn into beasts.
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In the prologue of The Mummy (1999), for his crimes, Imhotep is mummified alive and subjected to a curse so terrible that it was never used on any other man. As a side effect of the curse, among the powers Imhotep would gain if he's resurrected would be the ability to bring forth the Ten Plagues.
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 The Mummy (1999)
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 Mystical Plague / int_2b8a9633
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In Undead or Alive, the "White Man's Curse" that causes its wild-west era victims to rise from the dead and hunger for human brains is revealed to be a spell cast by the medicine man Geronimo before his death at the hands of the U.S. Army.
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The Delphinus Parasite in Shin Megami Tensei: Strange Journey doubles as this and a Hate Plague. It's actually the inchoate form of the resident Demon Lord's soul.
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Implicitly in the Justice League episode "Fury", in which a rogue Amazon named Aresia unleashes a global plague that only affects men, even alien men like J'onn and Superman.
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Stand Still, Stay Silent: The "rash illness" turns its victims into horrific monsters. It is strongly implied to be connected to the resurgence of magic. In fact, the old world actually managed to cure the disease without too much trouble. It's just that wasn't enough to actually save anyone, because the mundane disease was merely the vector for the mystical one. People who took the cure did not mutate into monsters, but still inevitably suffered brain death, and then their spirits stuck around as angry ghosts.
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ANNO: Mutationem: In the past, the world underwent a crisis when the Mechanika Virus caused bodies of people to be turned metallic. Later on, the virus' origin is stated to be from Limen, an Eldritch Location that also brought dangerous phenomena which spread out into the world.
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 ANNO: Mutationem (Video Game)
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In A Practical Guide to Evil, villains are infamous for sometimes using- or at least trying to use- magical plagues.
Warlock, when faced with a revolutionary army which includes cavalry, proposes to unleash a plague on the horses- he has one lying around in his laboratory. Also, he is the creator of several other doomsday works, some of which could be plagues.
The Dead King uses plagues that kill and zombify all the infected.
The heroes too: at one point the Grey Pilgrim engineers and uses a plague that kills roughtly 3000 people to catch the Black Knight.
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In the Harry Potter series, there is a great deal of fear of werewolves due to misinformation and concern about the spread of Lycanthropy, a parallel to AIDS, which sufferers of are discriminated against. In Prisoner of Azkaban, Lupin resigns after Snape outs him, and in Order of the Phoenix, it is revealed that Lupin and Sirius already despise Umbridge due to some anti-werewolf legislation she wrote up that makes it near impossible for werewolves to find employment.
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In The Divine Comedy, falsifiers (which include alchemists, perjurers and counterfeiters) are punished in the last bolgia in the 8th circle of hell by being afflicted by horrible diseases.
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Seen in Oedipus Rex, being an adaptation of Oedipus the King (see Theatre below). After Thebes suffers a terrible plague, Oedipus asks a seer why the gods are punishing his people. He gets the unwelcome answer that it's his fault, as punishment for killing his father and marrying his mother.
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The Dresden Files claims that The Black Death was originally created by Fallen Angels through magic. The book Death Masks centers on Harry recovering a religious artifact before the Fallen can use it to create another plague.
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SCP Foundation: Most SCPs with the "infectious" tag fall under this.
There are several diseases that are spread not though any physical vector but are instead spread though information, which are known as memetic hazards. One example of this is a key. If you learn anything about what the key looks like, you are infected and one of three things will happen. Either you will kill yourself at the first opportunity and anybody who sees you die is infected, or you will go on a murderous rampage and anybody who sees your victims die is infected, and after killing enough victims you will disappear and infect anybody who hears what you say right before doing so, or you will become strangely happy and will be driven to infect other people by sharing information about the key even if you weren't directly infected by the key, and after infecting enough people you will disappear and temporarily leave behind an area that causes anybody who enters it to be infected as well.
There also are plenty of more normal diseases that simply have weird effects on people that are infected with them such as a disease that causes you to regurgitate useful objects when you need them or a herpes virus that causes you to hallucinate that you are trapped in a game of Skyrim whenever you have an orgasm.
A straighter example of this is SCP-217 ("The Clockwork Virus"), a virus that turns living things into clockwork, which is believed to be the breath of God by a cult of machine-worshipers.
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Supernatural: The Croatoan Virus, which turns people into rage-filled zombies, is demonic in origin. Specifically, it was developed by the Horseman Pestilence on Lucifer's orders in order to herald the Apocalypse.
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Tweeny Witches: As the light of the Sanctuary is fading away, a nameless disease begins to afflict the witches, leaving its victims powerless and bedridden.
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The Psi Factor episode "Death at Sunset" deals with an inexplicable disease which kills the inhabitants of a small town one by one.
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 Psi Factor
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Elden Ring has the Scarlet Rot, a horrifying pathogen with few cures (most of which boil down to "apply fire to affected area and hope everything else can survive without it") that causes the infected to rot alive and have Alien Kudzu grow on their bodies. And it can affect anything: Humans, animals, plants, dragons, crystalians (aliens who, as their name suggests, are made of stone), the soil, the sky, minds, and even metaphysical concepts like Great Runes. Gameplay suggests that the only things immune to the rot are fantasy robots and things that aren't really there in the first place (such as projections like Golden Shade Godfrey). The reason why the Rot is so unstoppable is because it's a manifestation of an Outer God sealed in the Lake of Rot, and the Demigod Malenia is its chosen one and Patient Zero. Luckily for the rest of the world, Malenia is such a determinator that she can contain the Rot within her own body with sheer willpower. Unluckily, she's been resisting it for so long without any rest that said willpower is seriously fraying, and even her best efforts can't stop her from being a Walking Wasteland on a good day.
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Nobody Saves the World: As it turns out, not only does the Calamity consume the land, it also takes hold of the people as well, covering them in fungal growths and leaving them without any eyes.
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In the Emberverse novels, contact with the bodily fluids of a follower of the Church Universal and Triumphant can cause these in the form of necrotic lesions, the pus from which is outright poisonous. It gets to the point that objects that have touched captured CUT adherents are routinely burned as a precaution. Even swords.
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In A Day of Fallen Night (prequel to The Priory of the Orange Tree, below), we see the first emergence of the draconic plague — only nobody knows what it is yet. It first appears in Hróth and begins with unusual redness in the fingers that spreads up the arms, eventually causing an unbearable burning sensation, violent madness, and death. Despite efforts to contain it, poor sanitation practices coupled with the spread by draconic creatures result in it spreading to locations worldwide. It is termed as "the burning" by some due to its symptoms.
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In The Sister Verse and the Talons of Ruin, this is what people think is initially happening, until the plague refuses to spread, and they realize that it's a conscious entity possessing people.
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In the Labyrinths of Echo series, Anavuayna is an ancient magic plague, borne out of the curse of an enraged Elven princess, that not only slowly liquifies the victim's body, bones and all, while the victim is fully conscious, but also destroys their soul on every level of existence.
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In the Captain Marvel (Marvel Comics) title starring Genis-Vell, an offhand comment by the narration states that the Black Plague was caused by the anguished scream of a Cosmic Entity.
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The Twilight Zone (1985): In "Many, Many Monkeys", Jean Reed speculates that she and everyone else afflicted with the plague of blindness are being punished because they have become monkeys who see, hear and speak no evil. She thinks that nature has turned a blind eye to humans because of their diminished humanity. Although Nurse Claire Hendricks initially dismisses this idea as preposterous, she later becomes convinced that Jean is correct, even after the government links the plague to the accidental release of bacteria.
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 The Twilight Zone (1985)
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In King of Thorn, "Medusa" is a disease that came from a meteorite; spreading across the globe and turning most humans into statues (and others into monsters). It's revealed to have a psychic vector; rather than a viral or bacterial one.
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In The Reaping, the town of Haven claims to be suffering the biblical plagues of Egypt, which is the reason Katherine is there. They are revealed to be Loren's angelic power.
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Tolkien's Legendarium:
The Silmarillion mentions a plague apparently sent by Sauron to weaken Gondor so he could regain control of Mordor.
A mystical plague is used in the same work to account for the death of Túrin Turambar's younger sister Lalaith.
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There also are plenty of more normal diseases that simply have weird effects on people that are infected with them such as a disease that causes you to regurgitate useful objects when you need them or a herpes virus that causes you to hallucinate that you are trapped in a game of Skyrim whenever you have an orgasm.
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 The Elder Scrolls V: Skyrim (Video Game)
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The "Severed" elves in Inverloch, so termed because they lack the connection with the spirits that grants magic and immortality. When more and more elves began to be born with the signs (white hair and gold eyes), the elves began to exile them starting at the age of twelve in hopes that it would prevent the affliction from spreading. It only made matters worse, leading to speculation from the exiles that it was a punishment inflicted by the spirits for the elves' arrogance and isolationism. They prove to be right.
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The plague of undeath that turns people into zombies in Warcraft III, preparing the way for a demonic invasion.
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Exalted features, among many others, the Great Contagion. Dug out of a dimensional nexus that instills insanity in all those who view it without proper protection by one of the Deathlords, it killed about 90% of Creation on the first go. To clarify; not 90% of Creation's people, 90% of everything. Plants, animals, spirits, gods... anything that could basically constitute "alive" in Creation was fair game. On top of that, the disease was so infectious that mystically observing it was capable of contracting it. The only thing that stopped it from finishing the job was one of the other Deathlords inviting The Fair Folk in to finish the job; the chaotic energies of the Wyld that came with the invasion actually bolstered the immunities of the survivors.
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In the Dragon Age: Origins DLC "Warden's Keep", Avernus' research into the Taint suggests that it's alien to Thedas, with its true origins unknown even to the denizens of the Fade, such as Spirits and Demons. Avernus believes that the key to understanding it is tied into whatever caused the corruption of the Black City.
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In The Priory of the Orange Tree, fear of the draconic plague is the reason for Seiiki's laws against almost any immigration (save for a few Mentish traders restricted to one port city). It runs rampant in Yscalin following the king's conversion to wyrm-worship. Loth has to deliberately infect himself to escape the country with a piece of vital information and experiences the unpleasant symptoms: reddening hands, fever that escalates to a burning sensation, and malaise. Fortunately, he reaches his destination — which has a cure — in time.
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Dungeons & Dragons:
The Judges Guild adventure "Verbosh" had a new spell called "Plague" which causes 20-70% of the population in a 1 mile square area to be incapacitated for 1-4 weeks as well as killing many of them.
The 2E supplement Tome of Magic. The 7th level priest spell Breath of Death (reversed Breath of Life) affects an entire community. Anyone who fails a saving throw vs. death magic is infected with a disease that is fatal in 1-6 weeks.
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In the Book of Exodus, a couple of the Plagues of Egypt, which God called to force the Pharaoh to free his Jewish slaves, count: the plague of pestilence (which only affected livestock) and the plague of boils (skin disease).
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 Book of Exodus
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In The Traitor Son Cycle, the Big Bad crafts a curse that spreads and behaves like a deadly disease. It manages to scour two countries before a cure (also magical) is found.
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The Crimson Shadow: Greensparrow created a plague by magic to devastate Eriador so he could conquer it more easily.
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Sweet & Bitter Magic: Dark witches have unleashed ones twice by the time of the story. In the second case, it leeches away people's memories and joys, leaving them empty shells, before their bodies wither away too until they die. The second plague turns out to be the accidental side effect from the dark magic being used, not a deliberately inflicted one.
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The Tough Guide to Fantasyland: Natural plague is unknown (possibly due to a lack of bacteria or viruses). Magical plagues though are common tools of the Dark Lord and his minions. Due to this, it isn't caught by those not specifically targeted (like the protagonists).
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Knights of the Old Republic: The rakghoul disease is really the continuing spell from an ancient Sith sorcerer who used it to create an army of slaves who could function as skilled warriors and pilots, but were otherwise mindless. It's still around because it's spread by bite.
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Alien Weaponry's "Urutaa" (literally "plague" in M�ori) speaks of the epidemic that broke out among the M�ori-speaking Ngati Uru tribe after an 1808 visit by the brig Commerce commanded by James Ceroni, which they believed was a curse placed on them by Ceroni after he accidentally dropped his pocketwatch in the harbor.
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In the Visionaries episode "Horn of Unicorn, Claw of Dragon", a Magical Plague strikes Prysmos, affecting all but one of the Spectral Knights and up to five of the Darkling Lords. In this case, the precise cause of the Plague is unspecified, though Merklynn does say that he foresaw it coming and tried (unsuccessfully) to send the Darkling Lords on a quest for the ingredients (the unicorn's horn and dragon's claw referred to in the title) needed for a healing spell.
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Chasing Dragons: As the Fourth Slave War breaks out between the Abolitionist Alliance and the Valyrian League, Arthur Dayne employs a warlock to unleash a magically enhanced plague on King's Landing to keep Westeros too distracted to potentially join the war on the Alliance's side.
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The Song of the Lioness quartet has one early on: the Sweating Sickness is sent by an evil duke in hopes that it will weaken the kingdom and kill everyone who stands in his way to the throne.
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The Burning Kingdoms: The rot is a mysterious disease that affects both crops and humans, turning them tree-like over time. In humans, this means they start turning partly to wood and leaves, which eventually kills them unless arrested by those with power over plants. Sacred wood also can slow but not stop it, so sufferers that can wear beads of this.
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This is shown in Oedipus the King: Oedipus's actions (killing his father, marrying his mother) unknowingly bring blight and plague ("miasma") to his people. Crops do not grow, stock animals die off, and women suffer from infertility, all because Oedipus's actions went against classical concepts of morality.
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Mystical Plague
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In Dishonored, the rat plague initially was a virulent plague that the Spymaster brought from the Pandyssian Continent to wipe out the poor in Dunwall. Granny Rags seems to spread the plague by summoning more and more rats to areas. You can too if you go the High Chaos route.
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The Astral Plague in Tales From My D&D Campaign isn't a disease in the most technical sense of the word, as it doesn't seem to be contagious. Caused by exposure to the astral radiation from active Ytarran Teleportation Portals, the Plague wiped out the entire Ytarran race within a generation. More recently, the heroes have become infected, though they are at present shielded from the effects by a friendly spirit. However, the protection won't last forever, and the party will eventually need a cure.
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Elemental Masters: In Phoenix and Ashes, Alison summons a disease elemental and sets it loose; it's implied that this caused the 1918 H1N1 pandemic.
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The Elder Scrolls:
In the series backstory, the Thrassian Plague ravaged Tamriel in the 1st Era. Created by the "slug-men" Sload of Thras, the "coral kingdom" to the southwest of Tamriel, who are known to excel as necromancers and Evil Sorcerers. The Thrassian Plague killed more than half of Tamriel's population. In response, the nations of Tamriel formed the All-Flags Navy, which ravaged Thras, killed all of the Sload it could find, and finally sunk Thras beneath the sea. (The Sload survived, and would raise Thras to the surface once again, but never again tried something as ambitious as the Thrassian Plague) Unsurprisingly, Peryite, the Daedric Prince of Pestilence and Tasks, is rumored to have been associated with the creation of the plague.
Also from the backstory, the Knahaten Flu ravaged Tamriel in the 2nd Era for a period of about 40 years. It is attributed to an Argonian shaman who created the plague by manipulating the spores of the Hist in retaliation for the awful treatment of his people by the other races. Other sources claim that it was a natural disease, but the general distrust of the Argonians throughout Tamriel combined with the fact that Argonians were immune to the disease made the "Argonians caused it" story more popular. The Flu is believed to have completely wiped out the Lilmothiit "Fox Folk" and the Kothringi silver-skinned menfolk, both formerly native to the Black Marsh.
Morrowind:
Dagoth Ur's Blight, which spreads via Blight Storms and his minions. It can inflict crippling blight diseases and, most importantly, the Corprus Disease. The Corprus Disease is actually a curse of Dagoth Ur's (essentially divinity channeled from the Heart of Lorkhan), which brings those inflicted under his influence. It brings with it a nasty case of Body Horror and deteriorating mental functions.
The Crimson Plague in Tribunal is not a standard disease, but a mystical one spread by the powerful lich Gedna Relvel. You'll need to kill her in order to stop it, and it's no easy task.
In Skyrim, Peryite's Daedric quest involves hunting down and killing the leader of a group of his rogue followers who've been inflicted with such a plague. Before going rogue, Peryite intended to have these followers spread a this plague to "cover the world" with his "blessing".
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One Piece: Doc Q of the Blackbeard Pirates is revealed to have eaten a Devil Fruit that gives him the ability to create and spread diseases of which are of the more fantastical variety
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In the Rugrats "Passover" special, Moses (Tommy) unleashes plagues on Pharaoh (Angelica) to make her let the babies go. Of course, this being a kid's show, the plagues are downplayed to be mere annoyances to the Pharaoh while the more horrific ones aren't shown. The final plague is also played out different, with it being said that the first born of every household would be "taken away"; upon realizing that this included her, Pharaoh agreed to let everyone go if Moses called the plague off.
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In the Sword of Truth book Temple of the Winds, the Imperial Order unleashes a plague, based on The Black Death and made much worse by magic, on the heroes' capital city. For bonus Kick the Dog points, Emperor Jagang deliberately infects a group of young children as patients zero.
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The Lord of the Rings: The Rings of Power: The Southlands are affected by a mysterious black goo that sickens the vegetation and the animals. Several episodes later Lindon also is affected by this black goo.
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Magic: The Gathering has the disease Phyresis, spread via contact with Glistening Oil. The oil inevitably changes any organic life it encounters into Phyrexians, biomechanical monsters one card refers to as "An amalgam of living metal and dead flesh." Symptoms include the destruction of the patient's soul, snuffing their Planeswalker Spark (if they had one) and religious fervor over spreading the perfection of the oil far and wide. It gets worse. Phyrexians produce more oil, and so even a single drop can Doom an entire world (and, canonically, did doom the plane of Mirrodin). As an added bonus, Phyrexians dabble in the creation of mundane plagues to target specific populations, as shown off in the cards Spreading Plague, Engineered Plague, and Plague Engineer.
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Darkest Dungeon: The Crimson Curse is a debilitating infection that has two mystic properties; it cures every other disease, and it can't be cured unless a Courtyard boss is killed. The cutscenes make it clear that the infection is supernaturally tied to both the Vampire Countess and the Final Boss.
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Trollhunters: Claire contracts a nasty cold in the Season Two finale; coughing, sneezing, and Exhausted Eye Bags from overuse of her staff.
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The Filth of The Secret World. Essentially the Dreamers' will to awaken made manifest through their reality-warping powers, it exists to corrupt any being it touches and convert them into a subservient mutant dedicated to releasing the Dreamers from captivity (which would cause a Dream Apocalypse). For good measure, it takes a variety of forms throughout the setting: along with its common "tentacled black ooze" form, it also appears as toxic gas, weird weather, eldritch graffiti, radio signals... and, according to Dr. Klein, the historical epidemic popularly known as the Black Death.
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JoJo's Bizarre Adventure: It's stated at the beginning of Stardust Crusaders that only the strong-willed can control their Stands, and those lacking the proper Heroic Resolve develop a fever that will kill them, the latter happening to Jotaro's mother Holly and Josuke prior to the events of Diamond is Unbreakable.
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At the start of Neverwinter Nights, Neverwinter is in the grip of one of these. Curing it requires body parts from four magical creatures shipped from Waterdeep. Which are promptly stolen by the group behind the plague after they arrive, forcing the Player Character to spend the first chapter recovering them.
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Morrowind:
Dagoth Ur's Blight, which spreads via Blight Storms and his minions. It can inflict crippling blight diseases and, most importantly, the Corprus Disease. The Corprus Disease is actually a curse of Dagoth Ur's (essentially divinity channeled from the Heart of Lorkhan), which brings those inflicted under his influence. It brings with it a nasty case of Body Horror and deteriorating mental functions.
The Crimson Plague in Tribunal is not a standard disease, but a mystical one spread by the powerful lich Gedna Relvel. You'll need to kill her in order to stop it, and it's no easy task.
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 The Elder Scrolls III: Morrowind (Video Game)
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The plot driver in The Legend of Dick and Dom; the heroes are collecting Plot Coupons to make a magic potion to cure a plague. They discover in season two that it was magic, caused by the Big Bad.
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In Unsounded, regions in the nation of Alderode are afflicted by the Weeping Plague, which somehow spreads by making eye contact with a sufferer.
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The Age of Misrule: In The Queen of Sinister, magic has come back, technology has failed, and there is something lurking beyond even the mystical otherworlds of the dead and the gods that kinda, sorta, wants to destroy humanity utterly. A mystical plague that kills human life essence itself (basically 100% fatal, and dissolves its victims flesh leaving them just a load of pus inside a bag of skin and since it comes from the otherworld there is no known vector, source, or cure for the disease) is the chosen tool for this book. Too bad for it that two of the early victims were the son and husband of a woman that is an unknowing mystical champion of humanity, and the plague which was supposed to destroy her wakes that mystical potential. Nice Job Fixing It, Villain.
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In Warhammer and Warhammer 40,000, cultists of the Plague God Nurgle are granted powers to create and spread disease. The most feared among them is Nurgle's Rot, which has no consistent symptoms, can't be cured by natural means, and is said to consume the souls of the afflicted.
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Dragon Age: Inquisition reveals that Red Lyrium is lyrium tainted by the Blight. This has disturbing implications: since the Blight only affects living things, lyrium is alive, meaning using it is just another form of Blood Magic. The fact that Red Lyrium is found in the Primeval Thaig, which predates the First Blight, hints that the Blight existed long before the Darkspawn appeared. It didn't start with them.
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Star Wars (Marvel 1977) has the Crimson Forever, whose name is rather contrived — "D-dead! Everyone on board, Commander! Most of them fallen at their stations... their entire bodies turned that terrible crimson...! Even their eyes...! All open... staring... like they were looking straight on into forever...!" Luke and a squadron of pilots immediately put on masks and set up quarantine but still fell ill themselves after one of them found a red gem. It turned out there were two such gems, life-forms from beyond this galaxy who were mates, and who reacted to being separated by radiating anguish that manifested as illness and dropped people into comas deep enough that even the best medical tech was fooled. The shock of seeming to contract such a disease made most people die for real, but since Luke had had a fever-dream that gave him insights on what to do, he revived when the gems were reunited.
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Mystical Plague
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One rise scenario from All Flesh Must Be Eaten has the PHADE virus, which is the zombie plague... as an STD. The whole thing started when a guy was so bereaved about the loss of his girlfriend, he used necromancy to bring her back for one last fling. And then he decided he wasn't that into her, and slept with someone else, and it just spread from there.
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Mystical Plague
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Circle of Magic: Briar's Book (or The Healing in the Vine, depending on where you live) features one called the Blue Pox. Rather than being created deliberately, it's caused accidentally by improper disposal of magical potions.
 Mystical Plague / int_ca5cb239
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Mystical Plague / int_ca5cb239
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Mystical Plague
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Ōkami: When you arrive at Sei-An City, you find the citizens all seriously ill from a disease that seems to be originating from a thick green mist covering the city. Worse, the queen seems to be doing absolutely nothing to help. It's caused by a demon who has possessed the emperor, infecting him with some sort of illness and leaving him bedridden as he exhales the infectious mist.
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 Mystical Plague / int_d57d722e
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 Ōkami (Video Game)
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Mystical Plague / int_d57d722e
 Mystical Plague / int_d736423c
type
Mystical Plague
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The Rigel Black Chronicles draws on its source material for the Sleeping Plague, but it works quite differently and has different aims. It's not meant to kill anyone, just render a large number of children comatose and cause a public relations disaster for Dumbledore, weakening his political influence so that Riddle can push legislation through.
 Mystical Plague / int_d736423c
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Mystical Plague / int_d736423c
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Mystical Plague
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The Riftwar Cycle: In The King's Buccaneer, the Overlord of the City of the Serpent River works with some Pantathian serpent priests to kidnap a couple of hundred people from the Kingdom, mostly women and girls. Then they create magical duplicates of the prisoners and infect the duplicates with a magically created plague that is spread by contact and is almost always fatal. Then they send the prisoners back to the Kingdom, to the Western Realm's capital city of Krondor.
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Mystical Plague / int_e2b86487
 Mystical Plague / int_e59216c7
type
Mystical Plague
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In The Gamer's Alliance, the Blood Fever is a disease that is fatal to elves as it eats their blood cells from within and makes blood erupt from their bodies in the later stages. At first it seems like a natural plague, but over time and some investigations later it becomes apparent that the plague may in fact have a magical origin and has been created for a special purpose in which elven demise plays a part.
 Mystical Plague / int_e59216c7
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Mystical Plague / int_e59216c7
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Mystical Plague
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In the backstory of NieR, the sudden appearance of a large white humanoid figure and a dragon in Tokyo's Shinjuku District causes a disease called "White Chlorination Syndrome" to appear. This disease, which either turns humans into mindless monsters, or pillars of salt, sends humanity to near extinction, and the events of the game happen thousands of years after this.
 Mystical Plague / int_e5da461b
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 Mystical Plague / int_e5da461b
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Mystical Plague / int_e5da461b
 Mystical Plague / int_e6267766
type
Mystical Plague
 Mystical Plague / int_e6267766
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Star Wars Legends:
Star Wars (Marvel 1977) has the Crimson Forever, whose name is rather contrived — "D-dead! Everyone on board, Commander! Most of them fallen at their stations... their entire bodies turned that terrible crimson...! Even their eyes...! All open... staring... like they were looking straight on into forever...!" Luke and a squadron of pilots immediately put on masks and set up quarantine but still fell ill themselves after one of them found a red gem. It turned out there were two such gems, life-forms from beyond this galaxy who were mates, and who reacted to being separated by radiating anguish that manifested as illness and dropped people into comas deep enough that even the best medical tech was fooled. The shock of seeming to contract such a disease made most people die for real, but since Luke had had a fever-dream that gave him insights on what to do, he revived when the gems were reunited.
Knights of the Old Republic: The rakghoul disease is really the continuing spell from an ancient Sith sorcerer who used it to create an army of slaves who could function as skilled warriors and pilots, but were otherwise mindless. It's still around because it's spread by bite.
 Mystical Plague / int_e6267766
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Mystical Plague / int_e6267766
 Mystical Plague / int_ea4c5e89
type
Mystical Plague
 Mystical Plague / int_ea4c5e89
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Dark Shores: The blight from Dark Skies is first shown as foul-smelling rivers of black goo flowing through the countryside but then it turns out that any closer contact with it turns living beings into zombie-like creatures, devoid of any rational thought and (according to Grand Master Quindor) any life.
 Mystical Plague / int_ea4c5e89
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Mystical Plague / int_ea4c5e89
 Mystical Plague / int_ea4f62db
type
Mystical Plague
 Mystical Plague / int_ea4f62db
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Family Guy: In "If I'm Dyin', I'm Lyin'", Peter claims to have healed Chris of a disease he made up, which convinces the town that he's a divine healer, and he milks their worship of him for all it's worth. However, this makes God smite the Griffins with plagues based on those He cast upon Egypt, including darkness (the light bulbs going out), gadflies (Brian getting fleas), boils (Chris getting acne) and blood (Stewie's bath water turning to blood).
 Mystical Plague / int_ea4f62db
featureApplicability
1.0
 Mystical Plague / int_ea4f62db
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1.0
 Family Guy
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Mystical Plague / int_ea4f62db
 Mystical Plague / int_ec63f5fa
type
Mystical Plague
 Mystical Plague / int_ec63f5fa
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In the universe of The Last Witch Hunter, The Black Death isn't a natural disease, but a magical plague created by the Witch Queen as her take on Apocalypse How.
 Mystical Plague / int_ec63f5fa
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1.0
 Mystical Plague / int_ec63f5fa
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 The Last Witch Hunter
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Mystical Plague / int_ec63f5fa
 Mystical Plague / int_ed480be
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Mystical Plague
 Mystical Plague / int_ed480be
comment
The Hands of the Emperor: Whatever befell the island of Woodlark some time after the Fall. Whoever was affected died and turned into a monster. In the end, the island was quarantined and, to ensure the plague couldn't spread, the emperor burnt it down to the bedrock.
 Mystical Plague / int_ed480be
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1.0
 Mystical Plague / int_ed480be
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1.0
 The Hands of the Emperor
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Mystical Plague / int_ed480be
 Mystical Plague / int_ed72b3c9
type
Mystical Plague
 Mystical Plague / int_ed72b3c9
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Trauma Center (Atlus): Implied in Trauma Team, despite the developers otherwise trying to up the realism compared to previous games. The Rosalia Virus causes insanity via tumors in the brain, but oddly, two people infected know the name Rosalia, the name of the original carrier (who suffered none of the symptoms), before the disease was named or Rosalia's connection was even known. Also, Rosalia herself appears as a ghost to her childhood friend, and her last words imply that she knew her death would lead to the pandemic in the last part of the game.
 Mystical Plague / int_ed72b3c9
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 Mystical Plague / int_ed72b3c9
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 Trauma Center (Atlus) (Video Game)
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Mystical Plague / int_ed72b3c9
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Mystical Plague
 Mystical Plague / int_eed321b1
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Ars Magica: The spell "Curse of the Unportended Plague" starts a plague in a city over a period of 6-12 months. It will kill 10% of the city's population over a period of a few months.
 Mystical Plague / int_eed321b1
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Mystical Plague / int_eed321b1
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Mystical Plague
 Mystical Plague / int_eed50dcd
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In the Cronus Chronicles, one of our heroes, a British public school student named Zee, is sent to America to get away from one of these, not realizing he is in fact the carrier.
 Mystical Plague / int_eed50dcd
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 Cronus Chronicles
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Mystical Plague / int_eed50dcd
 Mystical Plague / int_f04d0f2b
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Mystical Plague
 Mystical Plague / int_f04d0f2b
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Heretic 2 has a mystic plague as a central part of the story, which was unleashed as D'Sparil's Dying Curse from the end of the first game. Mostly it causes death, insanity and violence, but there is mention of another version that can be used to control people.
 Mystical Plague / int_f04d0f2b
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1.0
 Mystical Plague / int_f04d0f2b
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 Heretic (Video Game)
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Mystical Plague / int_f04d0f2b
 Mystical Plague / int_f3e1f424
type
Mystical Plague
 Mystical Plague / int_f3e1f424
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Twice in Merlin (2008):
In the first season, Nimueh puts a creature into the water supply that sickens everyone in Camelot.
Later, a magical creature called a Lamia sickens an entire village AND the knights who go with Merlin when he is sent to try and stop it.
 Mystical Plague / int_f3e1f424
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1.0
 Mystical Plague / int_f3e1f424
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1.0
 Merlin (2008)
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Mystical Plague / int_f3e1f424
 Mystical Plague / int_f502a38a
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Mystical Plague
 Mystical Plague / int_f502a38a
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In one episode of The Smurfs (1981), Gargamel's Evil Plan is to spread a magical disease called the hopping cough, which causes a cough that makes the victims jump violently. (The idea is that if the Smurfs contract it, he can find and catch them more easily — or, in the non-Bowdlerised version, the illness is simply fatal if left untreated.) He even shows some smarts this time and plans to ambush them at the places where the ingredients for a cure can be found. Unfortunately for Gargamel, he eventually catches it himself while looking for them, and Papa Smurf does indeed manage to make the cure.
 Mystical Plague / int_f502a38a
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1.0
 Mystical Plague / int_f502a38a
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 The Smurfs (1981)
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Mystical Plague / int_f502a38a
 Mystical Plague / int_f97683ef
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Mystical Plague
 Mystical Plague / int_f97683ef
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Hollow Knight: The main threat in the game is a mysterious, terrifying plague that’s turning Hallownest into a Death World. Bugs afflicted with it are driven to violent insanity by it and get reanimated as monstrous husks after dying. It was created by the Radiance, the god who created bugkind, as a "divine" punishment after they stopped worshiping her and your character is an Empty Shell created to try and contain it.
 Mystical Plague / int_f97683ef
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1.0
 Mystical Plague / int_f97683ef
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Mystical Plague / int_f97683ef
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Mystical Plague
 Mystical Plague / int_f9fd68fc
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In Overlord II, the plague was caused by an event known as the Cataclysm that devastated the lands of the first game and gave rise to the Anti-Magical Faction. The ending reveals that the plague was caused by Florian Greenheart, an elf born without magic who tampered with the Tower Heart in an attempt to gain magical powers. With the help of Rose, he then created the Glorious Empire through the anti-magic sentiment of the humans following the Cataclysm while secretly gathering magic himself.
 Mystical Plague / int_f9fd68fc
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 Mystical Plague / int_f9fd68fc
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Mystical Plague / int_f9fd68fc
 Mystical Plague / int_faf84cd
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Mystical Plague
 Mystical Plague / int_faf84cd
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Vampire: The Masquerade - Bloodlines: A deadly disease spreading through vulnerable people in Los Angeles turns out to be the creation of a vampire Apocalypse Cult who cultivate it within their bodies.
 Mystical Plague / int_faf84cd
featureApplicability
1.0
 Mystical Plague / int_faf84cd
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 Vampire: The Masquerade - Bloodlines (Video Game)
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Mystical Plague / int_faf84cd
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Mystical Plague
 Mystical Plague / int_fe9b480e
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The Scum Villain's Self-Saving System: Ren Zha Fanpai Zijiu Xitong: The plague that sweeps through Jin Lan City causes the victim's flesh to rot down to the bones, eventually leaving nothing but a skeleton. The disease's progression can be slowed by wrapping oneself in black cloth and avoiding exposure to light and the elements, but straying too far from the city causes the disease to accelerate dramatically. It turns out that the plague was intentionally spread by demons known as sowers, who can infect any non-demon with their touch.
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The following is a list of statements referring to the current page from other pages.

 Mystical Plague
processingCategory2
Apocalyptic Index
 Mystical Plague
processingCategory2
Index Syndrome
 Mystical Plague
processingCategory2
Indexitis
 Mystical Plague
processingCategory2
Magic and Powers
 Mystical Plague
processingCategory2
Speculative Fiction Tropes
 Tweeny Witches / int_4603ea49
type
Mystical Plague
 The Sandman Universe (Comic Book) / int_4603ea49
type
Mystical Plague
 Knights of the Old Republic / Comicbook / int_4603ea49
type
Mystical Plague
 A Bug On A Stick (Fanfic) / int_4603ea49
type
Mystical Plague
 Ars Goetia (Fanfic) / int_4603ea49
type
Mystical Plague
 Be All My Sins (Fanfic) / int_4603ea49
type
Mystical Plague
 Black Star (Persona 5) (Fanfic) / int_4603ea49
type
Mystical Plague
 Chasing Dragons (Fanfic) / int_4603ea49
type
Mystical Plague
 Everfree Infection AU (Fanfic) / int_4603ea49
type
Mystical Plague
 Fallout: Equestria - Project Horizons (Fanfic) / int_4603ea49
type
Mystical Plague
 Foxfire (Fanfic) / int_4603ea49
type
Mystical Plague
 Foxfire (Rahar_Moonfire) (Fanfic) / int_4603ea49
type
Mystical Plague
 The Accidental Animagus (Fanfic) / int_4603ea49
type
Mystical Plague
 The End of Ponies (Fanfic) / int_4603ea49
type
Mystical Plague
 The Land of What Might-Have-Been (Fanfic) / int_4603ea49
type
Mystical Plague
 Infection / int_4603ea49
type
Mystical Plague
 Oedipus Rex / int_4603ea49
type
Mystical Plague
 [REC] / int_4603ea49
type
Mystical Plague
 The Last Witch Hunter / int_4603ea49
type
Mystical Plague
 The Reaping / int_4603ea49
type
Mystical Plague
 Undead or Alive / int_4603ea49
type
Mystical Plague
 Dragon Age (Franchise) / int_4603ea49
type
Mystical Plague
 Evillious Chronicles (Franchise) / int_4603ea49
type
Mystical Plague
 The Museum (Lets Play) / int_4603ea49
type
Mystical Plague
 Mushoku Tensei / int_4603ea49
type
Mystical Plague
 Mushoku Tensei: Jobless Reincarnation / int_4603ea49
type
Mystical Plague
 A Day of Fallen Night / int_4603ea49
type
Mystical Plague
 A Memory of Flames / int_4603ea49
type
Mystical Plague
 A Place So Wicked / int_4603ea49
type
Mystical Plague
 Angel Mage / int_4603ea49
type
Mystical Plague
 Beneath the Dragoneye Moons / int_4603ea49
type
Mystical Plague
 Book of Exodus / int_4603ea49
type
Mystical Plague
 Book of Job / int_4603ea49
type
Mystical Plague
 Books of Samuel / int_4603ea49
type
Mystical Plague
 Circle of Magic / int_4603ea49
type
Mystical Plague
 Death Masks / int_4603ea49
type
Mystical Plague
 Death Trance / int_4603ea49
type
Mystical Plague
 Demesne / int_4603ea49
type
Mystical Plague
 Dreamblood Duology / int_4603ea49
type
Mystical Plague
 Elemental Masters / int_4603ea49
type
Mystical Plague
 Labyrinths of Echo / int_4603ea49
type
Mystical Plague
 Malazan Book of the Fallen / int_4603ea49
type
Mystical Plague
 Mumbo Jumbo / int_4603ea49
type
Mystical Plague
 Mushoku Tensei: Jobless Reincarnation / int_4603ea49
type
Mystical Plague
 She Who Became The Sun / int_4603ea49
type
Mystical Plague
 Song of the Lioness / int_4603ea49
type
Mystical Plague
 Sword of Truth / int_4603ea49
type
Mystical Plague
 The Bone Palace / int_4603ea49
type
Mystical Plague
 The Burning Kingdoms / int_4603ea49
type
Mystical Plague
 The Crimson Shadow / int_4603ea49
type
Mystical Plague
 The Divine Comedy / int_4603ea49
type
Mystical Plague
 The Hands of the Emperor / int_4603ea49
type
Mystical Plague
 The Masque of the Red Death / int_4603ea49
type
Mystical Plague
 The Priory of the Orange Tree / int_4603ea49
type
Mystical Plague
 The Riftwar Cycle / int_4603ea49
type
Mystical Plague
 The Scum Villain's Self-Saving System: Ren Zha Fanpai Zijiu Xitong / int_4603ea49
type
Mystical Plague
 The Silmarillion / int_4603ea49
type
Mystical Plague
 The Soldier Son / int_4603ea49
type
Mystical Plague
 The Storm of M / int_4603ea49
type
Mystical Plague
 The Tough Guide to Fantasyland / int_4603ea49
type
Mystical Plague
 The Traitor Son Cycle / int_4603ea49
type
Mystical Plague
 The Wandering Inn / int_4603ea49
type
Mystical Plague
 The Years Of M / int_4603ea49
type
Mystical Plague
 ActionChatroom
seeAlso
Mystical Plague
 TheCardinalsBlades
seeAlso
Mystical Plague
 UQ Holder! (Manga) / int_4603ea49
type
Mystical Plague
 Alien Weaponry (Music) / int_4603ea49
type
Mystical Plague
 Evillious Chronicles (Music) / int_4603ea49
type
Mystical Plague
 CDT Adventure (Roleplay) / int_4603ea49
type
Mystical Plague
 Pathfinder Interesting Times (Roleplay) / int_4603ea49
type
Mystical Plague
 The Gamer's Alliance (Roleplay) / int_4603ea49
type
Mystical Plague
 Psi Factor / int_4603ea49
type
Mystical Plague
 Tale of the Nine Tailed / int_4603ea49
type
Mystical Plague
 The Legend of Dick and Dom / int_4603ea49
type
Mystical Plague
 Advanced Dungeons & Dragons 2nd Edition (Tabletop Game) / int_4603ea49
type
Mystical Plague
 All Flesh Must Be Eaten (Tabletop Game) / int_4603ea49
type
Mystical Plague
 Ars Magica (Tabletop Game) / int_4603ea49
type
Mystical Plague
 Invisible Sun (Tabletop Game) / int_4603ea49
type
Mystical Plague
 Malifaux (Tabletop Game) / int_4603ea49
type
Mystical Plague
 Pathfinder (Tabletop Game) / int_4603ea49
type
Mystical Plague
 Ptolus (Tabletop Game) / int_4603ea49
type
Mystical Plague
 The Strange (Tabletop Game) / int_4603ea49
type
Mystical Plague
 Warhammer (Tabletop Game) / int_4603ea49
type
Mystical Plague
 Oedipus the King (Theatre) / int_4603ea49
type
Mystical Plague
 Sera Myu (Theatre) / int_4603ea49
type
Mystical Plague
 ANNO: Mutationem (Video Game) / int_4603ea49
type
Mystical Plague
 Control (Video Game) / int_4603ea49
type
Mystical Plague
 Cube Escape (Video Game) / int_4603ea49
type
Mystical Plague
 Cythera (Video Game) / int_4603ea49
type
Mystical Plague
 Darkest Dungeon (Video Game) / int_4603ea49
type
Mystical Plague
 Darkest Dungeon II (Video Game) / int_4603ea49
type
Mystical Plague
 ENDER LILIES: Quietus of the Knights (Video Game) / int_4603ea49
type
Mystical Plague
 Final Fantasy XV (Video Game) / int_4603ea49
type
Mystical Plague
 Home Safety Hotline (Video Game) / int_4603ea49
type
Mystical Plague
 Last Rites (Video Game) / int_4603ea49
type
Mystical Plague
 Ni no Kuni (Video Game) / int_4603ea49
type
Mystical Plague
 Nobody Saves the World (Video Game) / int_4603ea49
type
Mystical Plague
 Octopath Traveler II (Video Game) / int_4603ea49
type
Mystical Plague
 Ōkami (Video Game) / int_4603ea49
type
Mystical Plague
 Red Dead Redemption: Undead Nightmare (Video Game) / int_4603ea49
type
Mystical Plague
 Spellstone (Video Game) / int_4603ea49
type
Mystical Plague
 Tears to Tiara 2 (Video Game) / int_4603ea49
type
Mystical Plague
 Thief (2014) (Video Game) / int_4603ea49
type
Mystical Plague
 Total War: Warhammer III (Video Game) / int_4603ea49
type
Mystical Plague
 Trauma Center (Atlus) (Video Game) / int_4603ea49
type
Mystical Plague
 Warcraft (Video Game) / int_4603ea49
type
Mystical Plague
 Wolfenstein: The Old Blood (Video Game) / int_4603ea49
type
Mystical Plague
 Lovebrush Chronicles (Visual Novel) / int_4603ea49
type
Mystical Plague
 Psycholonials (Visual Novel) / int_4603ea49
type
Mystical Plague
 Summer Rose Court (Visual Novel) / int_4603ea49
type
Mystical Plague
 DougDoug A.I. Invasion (Web Video) / int_4603ea49
type
Mystical Plague
 Aisopos (Webcomic) / int_4603ea49
type
Mystical Plague
 Stand Still, Stay Silent (Webcomic) / int_4603ea49
type
Mystical Plague
 Unsounded (Webcomic) / int_4603ea49
type
Mystical Plague
 Trollhunters / int_4603ea49
type
Mystical Plague
 Visionaries / int_4603ea49
type
Mystical Plague