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U.S. pharmaceutical advertisers face a difficult dilemma.note Direct-to-consumer advertising for prescription drugs is illegal in every country except the US and New Zealand Because of truth-in-advertising laws, any commercial giving indications for use of a prescription drug must give full disclosure of side effects. This means that drug commercials come in the following four flavors: "Healthoxine. Because you're worth it." The "reminder" commercial alternates shots of flowered meadows, senior citizens, nuclear families, and doctors, all while saying generally positive things about nothing in particular and mentioning the name of the drug. This evades both mentioning the side effects and what the drug actually does. This type is far less common these days; most commercials that still do this are the ones that give you help down there, because, due to social mores, they can't directly name what their product does anyway. Some of these ads tried to skirt the issue by naming another drug indicated for the same thing. "Ask your doctor if Happypills are right for you." This commercial actually does tell you what the pill is for, and then spends the rest of the commercial breaking the bad news gently: "If you have seasonal allergies, Mxyzptlkacine may be right for you. Side effects of Mxyzptlkacine are uncommon, and include headache, nausea, vomiting, death, dizziness, vaginal ejaculations, dysentery, cardiac arrhythmia, mild heart explosions, varicose veins, darkened stool, darkened soul, lycanthropy, trucanthropy, more vomiting, arteriosclerosis, hemorrhoids, diabeetus, virginity, mild discomfort, vampirism, gender impermanence, spontaneous dental hydroplosion, sugar high, even more vomiting, total scrotal implosion, brown, your mom, and mild rash." And yet, apparently, even after all this, enough people still want to get the drug that the cost of advertising is justified. Probably because while all the above side effects are being listed, the actors in the commercial are having the times of their lives. "Why live with the heartbreak of psoriasis?" A newer breed of commercial, the "help seeking" ad doesn't even mention the brand at all. Instead, it poses a public service announcement, offering a pamphlet you can receive — or now, a website you can visit — offering information on treatment options for a certain disease... "including a prescription treatment option." This one line is the real reason for the commercial; the pamphlet is an ad for the company's new drug, and the company wants you to read it since, in print, they're still allowed to hide the list of side effects in 1-point type. This kind of ad eventually becomes one for the drug in the pamphlet. "Are you at the end of your rope? There's hope." Another relatively new breed of commercial. The pitch here is to try to convince the viewer that the product works in a new way or is their last hope when everything else has failed. The commercial may even say that the product works in a different way than other types of medications that treat the particular condition. The hope here is to target those that are desperate for relief and therefore are willing to risk the long list of side effects in the hope that maybe this will be the product that finally gives them relief. Of course, in this case, the condition will likely be mentioned prominently, since how can the consumer know that they're at the end of their rope about a particular condition if they don't know what that condition is? Also, many commercials try to invoke a viewer's "Attention Deficit... Ooh, Shiny!" by having interesting, pretty scenes distracting them from the laundry list of side effects being rattled off. They do this by showing interesting situations like an asthma medication showing an elephant representing difficulty breathing following a man around during his day, or a world made of plumbing for a medication which helps you control frequent urination. Of course, if you've actually talked with your doctor about your problems, then your doctor would already have told you if Stupidoxin was right for you. But pharmaceutical companies continue to heavily advertise because you might have been too embarrassed to mention the problem to your doctor until you realized there was a treatment for it. Or you might not have considered it to be a problem at all until you saw the commercial with all the other people who were horribly embarrassed by their yellow toenails/hairy knuckles/insufficiently-lustrous eyelashes/etc, and realized that you needed to get the cure. Or even worse, you might have told your doctor about your problem but didn't request Stupidoxin by name, and so your doctor prescribed an equally-effective generic brand instead! (Somewhere an ad man is crying.) The prevalence of these commercials has resulted in this trope often being played for laughs, with the side effects being a ridiculously long list, the effects disproportionately bad compared to the condition the drug is supposed to treat, or the side effects becoming extremely bad, often including death, only to finish off with an incredibly mild condition like bad breath or a small rash. Compare and contrast What Were They Selling Again?, where specifics about the product are obscured unintentionally. Objects with more extreme or fantastic warnings fall under Do Not Taunt Happy Fun Ball. If the company selling the products is actively malicious it is May Contain Evil. |
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The Eric Andre Show introduces Lexivan, a drug that can help if your wheelchair-bound father falls down a flight of stairs. (Apparently, you take the medication, not your father.) No information about the drug is given, other than that the pills are lemon-lime flavored, and "What's the worst that can happen?" | |
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America's Funniest Home Videos gives you Imbesol, whose side effects apparently includes knocking yourself unconscious after taking said pill. | |
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The side-effects list was used in Becker as the main reason a split-personality patient didn't take his drugs - the "nice" personality was deathly afraid of the side effects. | |
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The Simpsons The episode "Barting Over" ends with Homer doing a commercial for a product that's both a hair growth formula and is a Viagra. In "Treehouse of Horror XXIX", the segment Geriatric Park features a commercial for Mr. Burns' new nursing complex where seniors are infused with dinosaur DNA. |
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In Brandy & Mr. Whiskers episode "Time for Waffles", they want whiter teeth, so they get a special gel from Gaspar. | |
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Lightning Returns: Final Fantasy XIII: An alchemist named Velno gives Lighting a potion mixed from two poisons called Nektar that she wants her to test in battle. She promises great things, though she can't say exactly what it does and warns her that "Side effects may include dementia, gangrene, sudden death and hair loss." | |
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Parodied by WandaVision in an ad for Nexus, "A unique anti-depressant that works to anchor you back to your reality. Or the reality of your choice." | |
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Packages from Planet X: Dan Zembrosky frequently receives alien packages from the titular planet, which he often toys around with before discovering that whatever they do usually has a catch. The Supersizer from "Fitness Crazed" gives its wearer a very muscular physique, which then turns into a large lump of mass in the wearer's body. The Intergalactic Extinguisher from "Return To Sender, Part 1". It disintegrates anything it zaps but causes the user to lose their outermost layer of skin. The Universal Telescope in "Astro-Blasters" can rearrange the location of astral bodies but causes the user's eye to morph in shape.note Strangely, this didn't happen with Calimary. The alien camera in "Dan TV", which intercepts all television broadcasts so the user is the only one on television. However, whenever someone turns their television set off, the user is zapped. The alien sunglasses in "The Iron Crown Affair" expose aliens to the wearer, but also causes temporary blindness. The alien scissors in "Bad Hair Day" can allow the user to style hair in a variety of ways, but all the cut hair congregates in the sewers and becomes a monster. The alien jumpsuit in "Last Dan Standing" makes its wearer able to evade any attack, but drains energy from the wearer, causing them to occasionally fall asleep. The alien board game from the appropriately-named episode "The Game", allows whoever interacts with it to be able to interact with objects in real life. The side effect is that it causes the user's hands to grow in size. The Re-Animator in "The Song Of The Mermoo" brings dead creatures to life but de-animates the user piece-by-piece each time it's used. The Healer Feelers in "Dr. Strangegloves" allow the wearer to be able to instantly diagnose and repair any damaged piece of technology they touch, but also cause the wearer to experience Rapid Aging. The Global Positioner in "True North Strong & Freezing" teleports the user to any place on the planet but also causes the user to swap heads with whoever else they use the device with. |
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Strong Bad's Cool Game for Attractive People: In "Homestar Ruiner", Strong Bad orders a free sample of Total Load in the mail. Use it on Strong Bad, and he contemplates using the stuff to help him win the Race to the End of the Race... until he reads the warning label and notes the side effects include "Fits of rage, excessive back hair, and mysterious pants issues", the last of which is apparently a deal-breaker. | |
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The Stray Kids song "Side Effects" lists the side effects to anti-anxiety medication, playing into the theme of self-doubt and paranoia. | |
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Arrested Development: In "Best Man For the Gob", we find out that the Funke family used to be a folk music group (Dr. Funke's 100% Natural Good-Time Family Band Solution) whose only purpose was to advertise various pharmaceuticals. Maeby's role in the band was reciting the side effects at the end of the song. "Switch Hitter" has it that one of the drugs promoted by the band (Teamocil) has been reintroduced to the market and Lindsey starts taking it for her latest issues. After she experiences some side effects, the Narrator mentions them. This also contains a sort-of inversion when Lindsey says hallucinations are a side effect and the Narrator says they aren't. |
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One Garfield Sunday strip has him watching a commercial for a supplement that promises to make men who use it more attractive to women. Then it warns that it could lead to abnormal hair growth all over the body, as well as uncontrollable blinking and knee-slapping. "What idiot would buy that product?", Garfield asks. Enter Jon, who's standing behind Garfield slapping his knee over and over again, blinking wildly, and with hair growing all over his body. | |
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In Pride & Prejudice: A Latter-Day Comedy, the Classics for Canines infomercial warns that "certain tracks on Wagner for the Vicious can trigger vicious violent behavior in German Shepherds". Later in the film, Charlie uses one of these CDs to make the police canines go crazy, allowing Darcy to escape. | |
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MADtv (1995) did a skit parodying this, not by concocting a ridiculous list of side effects, but by advertising the party drug MDMA (Ecstacy) as a Zoloft-like antidepressant. (It'll give you the serotonin boost you're looking for, but will also turn you into Dopamine Boy/Girl.) Although the side effects and disclaimers rattled off at the end are fairly ridiculous: | |
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Neurotically Yours: Foamy the squirrel quips about this. Foamy's friend Pilz-E rambled off a list of side-effects of all the medication he takes. He finishes off with death, but says "but I have a pill, to cure the death." |
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Grand Theft Auto: Grand Theft Auto: Vice City: A radio ad for hairspray mentions that using the product may cause dry mouth, dilated pupils, paranoia, heart palpitations, and nosebleeds — and also, your hair will look great. Grand Theft Auto: San Andreas: Another hair-care product, Castrodone, works by stopping testosterone production (as tendency towards balding correlates with high testosterone). As expected, the side effects involve making the user stereotypically "girly". |
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Fallout: New Vegas: The Sunset Sarsaparilla mascot Ol' Festus has a "silly ol' advisory" about the possible effects of drinking the soft drink including but not limited to "kidney damage, nausea, digital numbness, anxiety, loss of visual acuity, dizziness, occasional nosebleeds, joint inflammation, tooth decay, sore throat, bronchitis, organ rupture, and halitosis." He does note that you have to drink a "a helluva lot" of them to actually experience them.note They may have had to say this due to their Star Bottle Cap Contest, which they made up after the rumor about it started. | |
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Warcraft III: Clicking repeatedly on the Priest unit (the human side's healer) eventually results in him issuing the following disclaimer: "Side effects may include: Dry mouth, Nausea, Water retention, Painful rectal itch, Hallucinations, Psychosis, Coma, Death, and Halitosis. Magic is not for everyone, consult your doctor before use." | |
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And now parodied again on The Late Show with Stephen Colbert, which featured an ad for the show itself in the style of those for erectile dysfunction drugs, and warning that "if your Late Show lasts longer than 1 hour, you're watching James Corden." | |
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The music video for "Hell To Pay" by Miracle of Sound starts with the following: | |
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American Dad!: Do you sometimes feel irritable, restless, uneasy, sad, normal, or just plain not high? Maybe it's time to try crack! | |
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Ultra Fast Pony. A "gelatin swingset" serves as the Macguffin for one episode. Even though it's not even medicine, the series creator warns about its side effects in the video description. | |
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From Have Your Loved Ones Spayed or Neutered, repeated in Blue Collar Comedy Tour Rides Again: | |
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The drug Dylar in Don DeLillo's novel White Noise has a stated effect that's pretty weird in itself: eliminating the fear of death. However, its side effects are even stranger: causing the user to confuse words with the things they represent, resulting in hallucinations. And it doesn't work for its intended purpose anyway. | |
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Jazzapram, a birth control pill in Mulaney, has symptoms that include "Unmanageable hair, haplessness, cartoonishness, and an inability to know when to leave a room." It neatly explains the character flaws of a certain character. | |
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Grand Theft Auto: San Andreas: Another hair-care product, Castrodone, works by stopping testosterone production (as tendency towards balding correlates with high testosterone). As expected, the side effects involve making the user stereotypically "girly". | |
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Parodied with this Scratch animation that lampoons medication commercials, which advertises a cold medication known as "Deth". | |
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In Adrian Mole The Wilderness Years, Adrian obtains a prescription for medication for depression. He asks if there are any symptoms, and the chemist rattles off a long list, ending with "a bit depressing, isn't it?" Adrian agrees, and tears the prescription up. | |
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Grand Theft Auto: Vice City: A radio ad for hairspray mentions that using the product may cause dry mouth, dilated pupils, paranoia, heart palpitations, and nosebleeds — and also, your hair will look great. | |
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Saints Row 2: One of the Ultor Corporation's many commercials is an ad for a sleeping pill designed to treat adolescent night terrors. The ad plays soothing music and encourages the listener that "Their family deserves sweet dreams" before rattling off the list of side effects including seizures, chronic pain, jaundice, Asperger's and sudden paralysis, before ending with "...and night terrors"*The full list is "Impaired motor skills, back pain, neck pain, cold sweats, seizures, depression, narcolepsy, social anxiety disorder, jaundice, sudden paralysis, Asperger's syndrome, loss of hair pigmentation, delusions of grandeur and night terrors" Well that sounds like the key to a good night's sleep, doesn't it? | |
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Bloom County had a Sunday comic about the incredible dangers of snorting dandelions, which included spontaneous decapitation and turning into Woody Allen. In the last panel, Steve Dallas snorts them anyway. | |
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Brawl of the Objects has a list of side-effects from competing in the show. Shelly was implied to suffer from five of the symptoms. |
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We Happy Few: Uncle Jack likes to assure the citizens of Wellington Wells that any rumors that Joy causes increased aggressiveness, memory loss, paranoia, and other nasty side effects are completely untrue. | |
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Teen Titans (2003) had a parody of a magical drug, Zinthos, during a Trapped in TV Land episode. Raven usually intones "Azarath, Metrion, Zinthos" when using her powers, the commercial advertised Zinthos as from the makers of Azarath and Metrion. Some of the effects of this drug mirror her changes when she loses control of her powers: Multiple eyes, disturbing visions, fits of rage (though not bloating, cramping or loss of hair, thankfully). It also says not to get Zinthos wet, or feed it after midnight, a Shout-Out to the Gremlins movies. It also explains what happens if the viewer has trouble meditating ("Stop saying Zinthos and consult your ancient scrolls immediately.") | |
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Crash Bandicoot 4: It's About Time: The commercial for Dingodile's diner ends with a long warning regarding the quality of the food served there, noting that it may not necessarily meet the legal definition of "food" and a long list of potential side effects of consuming his fare that range from mildly irritating to much more worrisome to abstract and bizarre. | |
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Shrek 2: Puss rattles off a long list of side-effects of the Happily Ever After potion, which are written on the back of the label, and as such only visible after the potion has been drunk. Most notable is that in order to make the effects of the potion permanent, the drinker must obtain their true love's kiss by midnight. | |
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"Angie Tribeca": While Dr. Edelweiss chants the side effects of a sunscreen applied in the body of a victim, Angie and the rest of the gang are involved in a montage of scenes (playing sports, having dates or walking in the park) parodying the troop. | |
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A viral site for the Pixar movie WALL•E contains an ad for Xanadou, a medication to induce shopping euphoria. "Side-effects may include unpleasant taste, headache, drowsiness and dizziness, headaches, intestinal discomfort and cramping, temporary blindness, bleeding of the gums. Failure to use Xanadou during shopping specific excursions may result in a desire to wear drab clothing, redistribute wealth and property and attend socialist summer camps." | |
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In The Boondocks episode "Mr. Medicinal", Granddad received multiple prescription pills to relieve his stress. One of the pills had this type of commercial to promote it. The list of side effects is so ridiculous (severe loss of sexual performance is considered normal), he trashes all of the prescriptions and resort to smoking marijuana instead. Hilarity Ensues. | |
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Parodied in IISuperwomanII's "Types of Commercials". The first commercial parody is a medicine for sneezing. | |
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Pikmin 2: Louie tests out the edibility of every plant and animal he encounters, and his notes include the side-effects of the less edible specimens he taste-tested: Caustic dweevils are pronounced as being inedible, as side effects of eating them "include uncontrollable arm flailing and enthusiastic dishwashing". Louie advises against eating clover, as doing so "may result in nausea, headache, fever, fatigue, chest pains, paralysis, loss of bone density, moodiness, feral rage, sauciness, dilly-dallying, strokes of brilliance, and untimely doom". Glowstems are described as causing uncontrollable bouts of impromptu breakdancing. However, since they aren't actually plants but actually LEDs that the characters mistook for alien flora, it's likely that he got electrocuted trying to eat it and mistook the resulting muscle spasms for some strange food poisoning-induced dancing. |
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Sunset Overdrive: The last bit of fine print on the http://www.overchargedrink.com website used to promote the game, is this Long List of OverCharge Delirium XT side-effects and issues: | |
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In the episode "Any Which Way But Zeus" of The Venture Bros., some supervillains are forced to undergo an experimental procedure to inhibit their powers as a security precaution before a hero-villain summit. The list of side-effects is rattled off for them before they begin. In "Dr. Quymn, Medicine Woman", Dr. Venture reflexively quotes a side-effect list when explaining why he's searching for an alternative cure for impotence. |
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A short arc in The Boondocks comic strip concerns Granddad's attempts to figure out what the hell a drug commercial means when it says that its product will help you get "Back in the game". When Huey finally tells him, he gets sent to his room. (Making it even funnier, he's already in his room.) | |
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Portal 2: Repulsion gel was originally sold as a diet aid, but was pulled from shelves for "various reasons." Cave Johnson's voice-over hints at one side effect that probably contributed to the recall:note Thing is, it's a case of Now You Tell Me, as the test Chell just finished usually involves running under a gel spout and getting covered in Repulsion Gel. | |
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Elysium. When Max gets understandably annoyed that his robot parole officer has extended his parole, the robot asks if he wants a sedative, and a pop-up tray appears holding various colored pills. The tray lid is printed with the following warning: "Side effects may include: vomiting, diarrhea, nausea, dizziness, constipation, blurry vision, dry mouth, rash, increased heart palpitations, high blood pressure, violent seizures, and sudden death". Perhaps more than anything in the film, this warning shows the government's total disregard for the well-being of the citizens of Earth, as even a simple drug is so poorly regulated. | |
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Skullgirls: Valentine lists a few of these in one of her intro quotes. | |
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Saturday Night Live: Had a parody ad, this time for birth control. The voiceover is totally standard, but the video shows Amy Poehler repeatedly seducing men, women, and groups into her apartment, up to an entire wheelchair basketball team. Another skit parodied the usual commercial side effects announced when taking these drugs. It stated that among the side effects would include hallucinations, in which it then described EXACTLY what type of hallucinations you would have: a horrifying surrealist nightmare ending in a choice between two doors. The wrong door leads to hellish misery, but the right one to eternal joy... and a moist, itch-free scalp. And maybe mild flatulence. Another parody skit was for Chantix, a real-life drug to help with quitting smoking. It seems normal at first, with a pleasant voiceover talking over the loving interaction of a couple, up until they hear her mention 'homicidal thoughts and actions' as a side effect. Things keep getting comically worse as the husband gets more nervous about his wife murdering him, and the sketch ends with him running for his life and her chasing him. Although it's not for a prescription drug, the classic skit for "Happy Fun Ball" also parodied ads of this type...before there were ads of this type! (Of course, Happy Fun Ball is a completely different trope.) Similar to the above, "Jimmy Tango's Fat Busters" has Jim Carrey prancing about an infomercial stage to describe his "Ride the Snake" weight-loss method, which involves a combination of a suit of vibrating heat beads and crystal meth, and being extremely up-front the moment he hears the question about how, yes, it's illegal, and yes, there are side-effects on the user's body and mind, and they are various. All concerned describe their experiences, but they also lost weight ridiculously quickly. ("Probably too fast!") However, the man himself claims the main "side effect" is people not mockingly stuffing letters into his mouth like a mailbox; he then writhes a bit, something off and yells, "GET OFF!" Dwayne Johnson starred in a spoof ad for Xentrex, an erectile dysfunction drug made with questionably legal ingredients. Side effects listed were "fits of rage, acne, bleeding, baldness, blindness, whooping cough, hallucinations, coma, trouble swallowing, decrease in semen, increase in semen, nasal sores, constipation, vomiting, night terrors, amnesia and suicidal urges". Johnson then notes that those are just the side effects that they tell you about, mentioning that "I get the sweats, my bones are cold, my teeth are loose, my heart gets really hot, I can read minds and sometimes I wake up driving a stolen car." He still finds the medication worthwhile, though, because "Xentrex gave me my life back. Hail Satan!" |
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In Adventurers!, a Parody Commercial for magic ends with the warning: "Magic has been linked to low physical strength in test subjects. If after using magic you have any abnormal reaction, contact your local item shop." | |
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Robot Chicken offers a solution to those having the mood for bear sex, Bear-alis! The roofie pill needed to get a bear tranquilized and ready for bed. | |
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Children of Men. Close ups of Theo's cigarette packet show the health warnings have changed from focusing on the risk of cancer and heart disease to those more pertinent to the current crisis, now warning that smoking causes "INFERTILITY, MISCARRIAGE and IMPOTENCE". | |
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The LoadingReadyRun sketch "Xannathor" is based on this. "The H is silent, but you won't be." | |
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MID-LIFE! the Crisis Musical: "Side Effects" indicates that the fictional drug of Lipodexterine, meant to cure high cholesterol, may induce high cholesterol, blinking and rude outbursts, stigmata in men with comb-overs, comb-overs, false optimism when consumed with beers, leg spasms if Riverdance videos are watched, and multiple nipples in lab monkeys. And sudden stoppage may cause death... | |
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Ratchet & Clank Future: A Crack in Time: One ad that plays on the radio is Captain Qwark selling a revolutionary product called Q-Pore. | |
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The Daily Show with Jon Stewart: Jon Stewart mentioned one drug for restless leg syndrome with the side effect of "increased gambling". He argued that if he had a gambling addiction, he'd take a drug that gave him the "jimmie-legs", rather than the other way around. | |
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In the new version of The Shaggy Dog, Lance Strictland needs one of Dr. Kozak's serums to be able to walk and stay alive, Korak shows Strictland the genetically experimented snake in the laboratory, the snake rejuvenated thanks to the canine serum, but had side effects like; having a dog's tail and canine behaviors, which makes Strictland angry upon discovering this, as he does not want to end up as the snake. | |
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Unusually for a parody of this trope, in Something Happens Eternazec's side effects are logically tied to the primary effect...except for itchy armpits. | |
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Stellaris: In the Leviathans DLC, one of the trading enclaves sells a substance that helps colonists survive on alien worlds. Purchase it, and you'll also be given a Long List of potential side effects, including psychotic episodes, grain elevator explosions, unexpected supernova detonations, the collapse of the space-time continuum... | |
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Homestar Runner: In "Characters From Yonder Website", Strong Sad discovers all the other characters tripping on expired "Smarty Juice", a drink that lists side effects such as "drowsiness, euphoria, and unbelievably soothing children's programming." In "Halloween Hijinks", Homestar wonders if the "Homestar Runner Mysfit-steries" cartoon they just watched was the list of side-effects for Coach Z's old-man medication. |
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Negima! Magister Negi Magi does the gag with a forbidden spell designed to render its subject smart for six days: | |
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Middlemost Post: The side effects of being a cloud are apparently as follows: | |
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Zydrate from Repo! The Genetic Opera. Ask a gentern if Zydrate is right for you. | |
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MK's The Strange Case of Dr. Jekyll & Mr. Hyde: Jekyll needs to keep taking the Hyde Formula on a daily basis after trying it or he will die. | |
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Vampire: The Masquerade - Bloodlines features a cigarette warning with side effects including "jock itch", "alien invasion" and "the death of cute little puppies". | |
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In All I Know About Animal Behavior, I Learned in Loehmann's Dressing Room, During a sketch about medicine, Erma Bombeck mentions the "side effects" required disclosure. She then points out all the ways these disclaimers can ruin one's life, such as by giving one a choice between dealing with a drippy nose all day or losing one's job because one cannot drive under influence of the nose drops. | |
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